Study on Medications for Opioid Use Disorder (MOUD) and Overdose Prevention

The Medications for Opioid Use Disorder (MOUD) study is an 18-month observational cohort study conducted in outpatient settings without random assignment to OUD treatment. The study aims to achieve several objectives, including identifying factors that influence the type of OUD treatment offered to patients and the patient’s treatment choice. Additionally, the study aims to better understand patient and outpatient treatment facility factors associated with key OUD treatment outcomes, identify relevant antecedents or co-occurring conditions that could be addressed through primary prevention, and inform evidence-based practices and OUD treatment policies.

The data collected in the MOUD study is publicly available and includes various types of information such as the type of OUD treatment, substance use, drug overdose, health-related quality of life, socioeconomic status, side effects, resources utilization, COVID-related information, distance to treatment facility, treatment facility ID, region of treatment facility, and mortality outcomes. This comprehensive dataset provides valuable insights into the factors influencing OUD treatment outcomes and can be used to inform future research and policy decisions.

Patients from around the United States were included in the study, with data collected from outpatient treatment facilities in cities such as Birmingham, Boston, Chicago, Dallas, Denver, Los Angeles, New York, Phoenix, Seattle, and Washington, DC, among others. The study sample included 1,974 adults with OUD receiving various types of treatment at 62 outpatient facilities over the course of 18 months. Participants were followed from March 2018 through May 2021, with data collected through web-based, self-administered questionnaires at baseline and follow-up intervals.

Researchers analyzing the MOUD study data should be aware that CDC staff are unable to provide analytic or technical assistance. However, published manuscripts using the MOUD study data can provide valuable insights and guidance for researchers. These manuscripts cover a range of topics related to OUD treatment outcomes, barriers to retention in treatment, public health interventions, and the association between length of treatment and nonprescribed opioid use.

Accessing the publicly available MOUD study data is free of charge, and researchers can download data files, patient questionnaires, and codebooks to aid in their analysis. The codebook contains a list of variables, their labels, and distributions from baseline to 18 months post-baseline, while the patient questionnaires provide insight into the questions asked of enrolled patients. The datasets available include five CSV files from baseline to 18 months post-baseline, offering a wealth of information for researchers to explore.

Overall, the MOUD study provides a valuable resource for understanding and improving outcomes for individuals receiving treatment for OUD. By analyzing the data collected in this study, researchers can gain insights into the factors influencing treatment choices, outcomes, and barriers to retention, ultimately informing evidence-based practices and policies in the field of OUD treatment.

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